Image-guided Pap Test (ThinPrep). with reflex to HPV when ASC-US (Aptima)

Arbor Diagnostics

Test name: Gynecologic Pap Test, Liquid Based, Image-Guided, with Reflex to High Risk HPV if ASCUS

Specimen: Thin Prep Pap Test Vial

CPT Codes: 88175 (88141 added if reviewed by pathologist and 87624 added if reflexed)

Collection: A gynecologic sample is collected using a brush and plastic spatula as a cervical sampling system. Record the patient name and ID number on the vial, fully complete a specimen requisition, and forward to Arbor Diagnostics in a specimen bag.

Special Instructions and Considerations: Specimen must be processed within 21 days of collection. Specimen should not be collected within 1 week of menstruation. Excessive lubricant may interfere with sample adequacy.

Storage Instructions: Maintain at room temperature

Transport Instructions: Transport at room temperature

Causes for Rejection: Improperly labeled or expired vial, frozen specimen, specimen older than 21 days from collection

Limitations, Causes for Unsatisfactory Results: Sample collected near menstrual cycle or with excessive lubricant

Test Methodology: Hologic ThinPrep Liquid Based Imaging System. The high-risk HPV test is used for types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without differentiation of the individual type. This assay aids in the diagnosis of sexually-transmitted HPV infection and in the triage of patients with an ASCUS Pap smear result.

Arbor Diagnostics

References

Wilbur DC, Cibas ES, Merritt S, James LP, Berger BM, Bonfiglio TA. ThinPrep® Processor: Clinical trials demonstrate an increased detection rate of abnormal cervical cytologic specimens. Am J Clin Pathol. 1994 Feb; 101(2):209-214.PubMed 8116577

Manos MM, Kinney WK, Hurley B, et al. Identifying women with cervical neoplasia: Using human papillomavirus DNA testing for equivocal Papanicolaou results. JAMA. 1999 May 5; 281:1605-1610.PubMed 8116578

Arbor Diagnostics Dallas TX