High-Risk HPV

Diagnostic Testing Medical

Test name: High-Risk HPV

Specimen: Thin Prep Pap Test Vial

CPT Codes: 87624

Collection: Gynecological specimen collected in the PreservCyt Solution. Record the patient name and ID number on the vial, fully complete a specimen requisition, and forward to Arbor Diagnostics in a specimen bag.

Special Instructions and Considerations: Gynecological broom-type or endocervical brush/spatula collection devices should be used. Specimen should not be collected within 1 week of menstruation. Excessive lubricant may interfere with sample adequacy.  Must be processed within 30 days of collection.

Storage Instructions: Maintain at room temperature

Transport Instructions: Transport at room temperature

Causes for Rejection: Improperly labeled or expired vial, frozen specimen, or specimen older than 21 days from collection.

Limitations, Causes for Unsatisfactory Results:  Sample collected near menstrual cycle or with excessive lubricant

Test Methodology: A nucleic acid amplification test is used for the qualitative detection of 14 types of high-risk HPV (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68) without differentiation of the individual type.

Arbor Diagnostics Test List

References:

Manos MM, Kinney WK, Hurley B, et al. Identifying women with cervical neoplasia: Using human papillomavirus DNA testing for equivocal Papanicolaou results. JAMA. 1999 May 5; 281:1605-1610.PubMed 8116578

Stoler, M.H., T.C. Wright, Jr., J. Cuzick, J. Dockter, J. Reid, D. Getman, C. Giachetti. 2013. Aptima HPV assay performance in women with atypical squamous cells of undetermined significance cytology results. American Journal of Obstetrics & Gynecology. 208(2):144-145.

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